INTENDED USE
The Creatinine Test Strip work with the Dry Biochemical Analysis Meter (DBM-101) to measure the Creatinine (CR/CREA) concentration in whole blood, plasma and serum. For professional use.Creatinine is a breakdown product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body (depending on muscle mass) .Serum creatinine is an important indicator of renal health because it is an easily measured by product of muscle metabolism that is excreted unchanged by the kidneys. Creatinine measurements are used in the diagnosis muscle diseases or various kidney diseases such as nephritis and renal insufficiency.
                                                            MEASUREMENT RANGE


Test Type
Measurement Range
Creatinine (CR)
0.044~1.320 mmol/L (0.50~14.93 mg/dL)


* For creatinine, 1 mmol/L =11.31mg/dL
Results below the ranges will show “Lo”, and results above the ranges will show “HI”.
                PRINCIPLE AND REFERENCE VALUES
The Creatinine Test Strip use a timed-endpoint method to measure the Creatinine (CR)
concentrations in whole blood, serum or plasma. The system monitors the change in absorbance
at 620 nm at a fixed-time interval. The change in absorbance is directly proportional to the
concentration of metabolite in the specimen.
CR: Creatinine in the specimen are hydrolyzed to creatine by the action of creatininase. A
sequence of three coupled enzymatic steps using creatinase, sarcosine oxidase, and peroxidase  
causes the oxidative coupling of 4-aminoantipyrine to form a blue dye.
Reference values are listed in the chart below:
Tests
Desirable
Creatinine(CR)
Men: 0.070~0.115mmol/L（0.79~1.30mg/dL） Women:0.044~0.080mmol/L（0.50~0.90mg/dL）


Reference ranges may vary between laboratories. Every laboratory should establish its own
reference range as needed.CR levels will have big physiological fluctuations depending on food consumed or exercise.